Development of microfiber sensor in detecting glucose condition using a Box Behnken Design (BBD) approach and design expert

Zualkefli, Siti Maisarah (2024) Development of microfiber sensor in detecting glucose condition using a Box Behnken Design (BBD) approach and design expert. Project Report. Universiti Teknikal Malaysia Melaka, Melaka, Malaysia. (Submitted)

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Abstract

This study developed a microfiber sensor for detecting glucose levels. In recent years, microfiber sensors for detecting and analyzing glucose have become increasingly popular. Microfiber optical sensors have been shown great potential in this field, and wearable optical microfiber sensors for glucose monitoring have recently gained interest. These sensors offer advantages such as high sensitivity, small size, flexibility, and non-invasiveness, making them suitable for wearable applications. Various input parameters were considered when optimizing the sensor performance to enhance sensitivity, including wavelength, microfiber diameter, glucose concentration, and microfiber types. These optimization approaches were obtained using the Design of Experiments, with the expectation of improving the development of optical microfiber sensors for glucose detection. The application of Design Expert Software and the Box-Behnken Design optimization approach played a crucial role in systematically planning and analyzing trials, resulting in a deeper understanding of the correlations between variables and responses. The findings presented the solution of the best parameter to detect the glucose condition and it is the optimal solution for the given criteria.

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