Design of surface plasmon resonance sensor for urea detection

Sathiyanandan Elangovan, Ragu (2022) Design of surface plasmon resonance sensor for urea detection. Project Report. Universiti Teknikal Malaysia Melaka, Melaka, Malaysia. (Submitted)

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Abstract

In the past years, the invention of biomedical gadgets has driven a new level achievement inscience and technology. This can actually increase the chances to identify disease in early stage. Urea is a waste which is excreted by kidney can be detected using this Surface Plasmon Resonance (SPR) sensor. To detect urea, the material type and thickness is an important role here as it may affect the sensitivity. In this study, the SPR sensor is tested using two different material which is Silver (Ag) and Gold (Au) with thickness of material from 30nm to 50nm using optical wavelength of 633nm, 670nm and 785nm. This study is continued with Taguchi method to helps in comparing the materials with different wavelength and thickness easily. The SPR curve were compared with water layer initially then with gold and silver material by using Taguchi method. Winspall software is used in getting the SPR curve using refractive index and reflection coefficient. Minitab software then is used to transfer the data that obtained from winspall to display an overall combined curve for clear picture of comparison. The output of this study can be seen with the resonance angle and the FWHM which determine the sensitivity in detecting the presence of urea. The gold material with factor combination A3B3C3D2 shows the best sensitivity in detecting the urea more precisely when comparing to silver material in this study.

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