The Gene Exploration Of Chronic Diseases

Nurlayana, Muty (2013) The Gene Exploration Of Chronic Diseases. Project Report. UTeM, Melaka, Malaysia. (Submitted)

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Abstract

Coronary heart disease, diabetes, high blood pressure and chronic kidney are the most highly ranked chronic diseases. The diseases can also be represented by the gene. Furthermore, the gene expression is the way of getting information of gene from the protein. This protein will give the information of the diseases occur in the human body. Thus, the method of detecting diseases in human body is the genetic testing. The genetic testing must be proceeding but the probe set must be known. The probe set is the measurement in DNA Microarray. The Self-organizing map will be the technique chosen to find the best probe set to represent a gene. The gene is chosen based on the attributes and description taken to finalize the analysis. The gene code changes because of the order of mutation. Thus, the mutation of gene in human body really gives the picture of disease. Probe used to explain to make a measurement in a gene expression experiment. Probe-set is a package of two or more probes that are used to measure a molecular. The dataset will be preprocessing in term of probe set. The analysis phase gives the best picture in other to determine the visualization of the data. This chapter defines the techniques used in the MATLAB. The Unified identified matrix is used for the visualization of the self-organizing map.

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